Pressure effects in the synthesis of isomeric rotaxanes.
نویسندگان
چکیده
Pressure not only influences the yield in the synthesis of a two-station [2]rotaxane, it also determines the distribution of the co-conformational isomers. At high pressure cyclobis(paraquat-p-phenylene) is preferentially assembled around a monopyrrolotetrathiafulvalene unit, while at low pressure it is preferentially assembled around a hydroquinone unit.
منابع مشابه
Synthesis of Novel 4-[1-(4-fluorobenzyl)-5-imidazolyl] Dihydropyridines and Studying their Effects on Rat Blood Pressure
Objective(s) Calcium-channel blockers have an important role in the treatment of several cardiovascular disorders. Derivatives of 1, 4-dihydropyridine are one of the most potent calcium antagonists. In this study four novel ', 4-dihydropyridine calcium channel blockers were synthesized and their hypotensive properties were investigated in male rats. Materials and Methods Four 1, 4-dihydropyr...
متن کاملFacile Fabrication of Boron-Doped Titania Nanopowders by Atmospheric Pressure Chemical Vapor Synthesis Route and its Photocatalytic Activity
The Atmospheric Pressure Chemical Vapor Synthesis (APCVS) route is a process that can be used for the synthesis of doped-nanocrystalline powders with very small crystallite sizes having a narrow particle size distribution and high purity. In this study, APCVS technique was used to prepare boron-doped titania nanopowders. The effects of temperature, borate flow rate and water flow rate on the am...
متن کاملSynthesis and stabilities of peptide-based [1]rotaxanes: molecular grafting onto lasso peptide scaffolds.
The chemical synthesis of peptide-based [1]rotaxanes (lasso peptides) was achieved by [2]rotaxane formation followed by two chemoselective ligation reactions. Our approach enabled incorporation of various peptide sequences into a common rotaxane structure. The synthetic lasso peptides were characterized by NMR, chromatography, and partial degradation by proteases. A linear peptide epitope graft...
متن کاملSynthesis of fumaramide derived [3]rotaxanes as potential precursors for molecular boxes.
Three new fumaramide-derived [3]rotaxanes have been synthesized, with the aim of macrocycle linking to form a molecular box. In one case, a nine-component templated [3]rotaxane synthesis was accomplished in 40% yield. Rotaxane reduction resulted in an unexpectedly facile de-slipping process.
متن کاملRecent advances in the synthesis of ammonium-based rotaxanes.
The number of synthetic methods enabling the preparation of ammonium-based rotaxanes has increased very rapidly in the past ten years. The challenge in the synthesis of rotaxanes results from the rather weak interactions between the ammonium-containing rod and the crown ether macrocycle in the pseudorotaxane structure that rely mostly on O*H hydrogen bonds. Indeed, no strong base or polar solve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- Chemical communications
دوره 49 53 شماره
صفحات -
تاریخ انتشار 2013